/wp-content/uploads/BBOT_White_Logo.svg00eallison/wp-content/uploads/BBOT_White_Logo.svgeallison2024-08-11 23:24:282024-08-29 13:15:43BBO-8520, a First-in-Class, Direct Inhibitor of KRASG12C (ON), Locks GTP-Bound KRASG12C in the State 1 Conformation Resulting in Rapid and Complete Blockade of Effector Binding
/wp-content/uploads/BBOT_White_Logo.svg00eallison/wp-content/uploads/BBOT_White_Logo.svgeallison2024-08-11 23:23:022024-08-13 13:50:40Revealing the Mechanism of Action of a First-in-Class Covalent Inhibitor of KRASG12C (ON) and Other Functional Properties of Oncogenic KRAS by 31P NMR
/wp-content/uploads/BBOT_White_Logo.svg00eallison/wp-content/uploads/BBOT_White_Logo.svgeallison2024-08-11 23:22:122024-08-13 13:49:28Targeting RAS-Driven PI3Kα Activation in Human Tumors
/wp-content/uploads/BBOT_White_Logo.svg00eallison/wp-content/uploads/BBOT_White_Logo.svgeallison2024-08-11 23:21:062024-08-13 13:47:17Use of the Natural Nucleotide, GTP, is Essential for the Identification of Potent, Active-State KRASG12C Inhibitors That Bind in the Switch II Pocket
/wp-content/uploads/BBOT_White_Logo.svg00eallison/wp-content/uploads/BBOT_White_Logo.svgeallison2024-08-11 23:19:582024-08-13 13:48:09Targeting RAS-Driven PI3Kα Activation in Human Tumors
/wp-content/uploads/BBOT_White_Logo.svg00eallison/wp-content/uploads/BBOT_White_Logo.svgeallison2024-08-11 23:19:122024-08-13 13:47:53BBO-8520, a First-in-Class, Direct Inhibitor of KRASG12C (ON)
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